TY - JOUR
KW - Amino Acid Sequence
KW - Antibodies, Bacterial
KW - Antibodies, Monoclonal
KW - Antigens, Bacterial
KW - Base Sequence
KW - Cloning, Molecular
KW - Genes, Bacterial
KW - Humans
KW - Leprosy, lepromatous
KW - Molecular Probes
KW - Molecular Sequence Data
KW - Molecular Weight
KW - Mycobacterium leprae
KW - Recombinant Fusion Proteins
AU - Cherayil B J
AU - Young R A
AB - <p>The gene for a 28-kDa Mycobacterium leprae protein Ag, a major target of antibodies from patients with lepromatous leprosy, was cloned from a lambda-gt11-M. leprae DNA expression library and sequenced. Antibodies to this protein were detected in the serum of the majority of 15 individual lepromatous patients that were tested. The predicted amino acid sequence of the 28-kDa protein suggests that it is localized to the bacterial plasma membrane or cell wall.</p>
BT - Journal of immunology (Baltimore, Md. : 1950)
C1 - http://www.ncbi.nlm.nih.gov/pubmed/3058804?dopt=Abstract
DA - 1988 Dec 15
IS - 12
J2 - J. Immunol.
LA - eng
N2 - <p>The gene for a 28-kDa Mycobacterium leprae protein Ag, a major target of antibodies from patients with lepromatous leprosy, was cloned from a lambda-gt11-M. leprae DNA expression library and sequenced. Antibodies to this protein were detected in the serum of the majority of 15 individual lepromatous patients that were tested. The predicted amino acid sequence of the 28-kDa protein suggests that it is localized to the bacterial plasma membrane or cell wall.</p>
PY - 1988
SP - 4370
EP - 5
T2 - Journal of immunology (Baltimore, Md. : 1950)
TI - A 28-kDa protein from Mycobacterium leprae is a target of the human antibody response in lepromatous leprosy.
VL - 141
SN - 0022-1767
ER -