TY - JOUR KW - Animals KW - Armadillos KW - Dapsone KW - Florida KW - leprosy KW - Louisiana KW - Peptidyl-Dipeptidase A KW - Venezuela AU - Dhople A M AU - Howell P C AU - Williams S L AU - Zeigler J A AU - Storrs E E AB -

Serum angiotensin-converting enzyme activity was measured in 91 adult healthy and lepromatous armadillos before inoculation with M. leprae and at necropsises. Mean ACE values were significantly elevated in armadillos with leprosy and the degree of elevation was roughly proportional to the extent of infection. There was also significant difference in the serum ACE levels between Florida and Louisiana armadillos. The dapsone treatment resulted in bringing these levels to normal. Serial assays of serum, ACE provided information on the response of armadillos to dapsone therapy.

BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/3001195?dopt=Abstract CN - Infolep Library - available DA - 1985 Apr-Jun IS - 2 J2 - Indian J Lepr LA - eng N2 -

Serum angiotensin-converting enzyme activity was measured in 91 adult healthy and lepromatous armadillos before inoculation with M. leprae and at necropsises. Mean ACE values were significantly elevated in armadillos with leprosy and the degree of elevation was roughly proportional to the extent of infection. There was also significant difference in the serum ACE levels between Florida and Louisiana armadillos. The dapsone treatment resulted in bringing these levels to normal. Serial assays of serum, ACE provided information on the response of armadillos to dapsone therapy.

PY - 1985 SP - 282 EP - 7 T2 - Indian journal of leprosy TI - Serum angiotensin-converting enzyme in leprosy. VL - 57 SN - 0254-9395 ER -