TY - JOUR KW - Adult KW - Biopsy KW - Endothelium KW - Female KW - Humans KW - Inclusion Bodies KW - leprosy KW - Male KW - Microscopy, Electron KW - Middle Aged KW - Muscle, Smooth, Vascular KW - Mycobacterium leprae KW - Phlebitis KW - Pinocytosis KW - Veins AU - Mukherjee A AU - Misra R S AU - Sharma A K AB -
An ultrastructural study on vein biopsies from six lepromatous leprosy patients was carried out. The results showed that a) the lumen-lining bacillated cells were endothelial in origin due to the presence of specific Weibel-Palade endothelial cell granules; b) endothelial cells released Mycobacterium leprae into the lumen by exophagocytosis; c) M. leprae were able to grow and multiply in the endothelial and smooth muscle cells; and d) smooth muscle cells did not show any evidence of reaction due to the presence of M. leprae in their cytoplasm.
BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association C1 - http://www.ncbi.nlm.nih.gov/pubmed/3003213?dopt=Abstract DA - 1985 Dec IS - 4 J2 - Int. J. Lepr. Other Mycobact. Dis. LA - eng N2 -An ultrastructural study on vein biopsies from six lepromatous leprosy patients was carried out. The results showed that a) the lumen-lining bacillated cells were endothelial in origin due to the presence of specific Weibel-Palade endothelial cell granules; b) endothelial cells released Mycobacterium leprae into the lumen by exophagocytosis; c) M. leprae were able to grow and multiply in the endothelial and smooth muscle cells; and d) smooth muscle cells did not show any evidence of reaction due to the presence of M. leprae in their cytoplasm.
PY - 1985 SP - 571 EP - 6 T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association TI - Ultrastructure of leprous phlebitis. VL - 53 SN - 0148-916X ER -