TY - JOUR KW - Hansen’s disease KW - a typical presentation KW - cold abscess KW - sporotrichoid KW - Diagnosis KW - diagnostic challenges AU - Aswini R AU - Varghese AE AU - Benny B AU - Zacharia M AU - Ajithkumar K AU - Sajeev S AU - Gopal D AB -

Hansen’s disease (HD) is known for its varied clinical presentations. We report a case of a 28-year-old male presenting with multiple asymptomatic subcutaneous cysts in a sporotrichoid pattern on his left lower limb. The patient presented without obvious neurological deficits, which misled the diagnosis. Relevant investigations and non-response to empirical therapy helped to rule out various differential diagnoses, including atypical mycobacterial infections, sporotrichosis and phaeohyphomycosis. The diagnosis of Hansen’s disease was achieved through MRI and highresolution ultrasonography (HR USG) by demonstrating nerve thickening and nerve abscesses along the common peroneal and superficial peroneal nerve respectively, and nerve conduction studies, which revealed absent sensory neural action potentials in the superficial peroneal nerve and reduced amplitude with prolonged latency of the common peroneal nerve’s motor action potential. This case highlights an unusual presentation of Hansen’s disease and the role

BT - Leprosy Review DO - 10.47276/lr.96.4.2025079 IS - 4 LA - ENG M3 - Case Report N2 -

Hansen’s disease (HD) is known for its varied clinical presentations. We report a case of a 28-year-old male presenting with multiple asymptomatic subcutaneous cysts in a sporotrichoid pattern on his left lower limb. The patient presented without obvious neurological deficits, which misled the diagnosis. Relevant investigations and non-response to empirical therapy helped to rule out various differential diagnoses, including atypical mycobacterial infections, sporotrichosis and phaeohyphomycosis. The diagnosis of Hansen’s disease was achieved through MRI and highresolution ultrasonography (HR USG) by demonstrating nerve thickening and nerve abscesses along the common peroneal and superficial peroneal nerve respectively, and nerve conduction studies, which revealed absent sensory neural action potentials in the superficial peroneal nerve and reduced amplitude with prolonged latency of the common peroneal nerve’s motor action potential. This case highlights an unusual presentation of Hansen’s disease and the role

PB - Lepra PY - 2025 SP - 1 EP - 5 T2 - Leprosy Review TI - Hansen’s disease presenting as sporotrichoid subcutaneous cysts UR - https://leprosyreview.org/article/96/4/20-25079 VL - 96 SN - 2162-8807 ER -