TY - JOUR KW - Community stigma KW - Leprosy KW - Iris pearls KW - Hansen's disease KW - Eye in leprosy AU - Katoch S AU - Chandel T AU - Tuli R AU - Sharma G AU - Chauhan PS AU - Minhas N AB -

This cross-sectional descriptive study was carried out in the Department of Ophthalmology at Dr RPGMC Tanda Kangra (H.P.) over a one-year time period (2023). The total number of patients studied was 37 (74 eyes), including 16 new cases and 21 old cases.

The M:F ratio was 5:1. Most patients were in age groups 35–50 and >50 (43% each). The most common classification was lepromatous leprosy (51%), followed by borderline leprosy (30%); lepromatous cases had higher ocular disability than other groups.

65% of patients had ocular involvement related to leprosy. Eyelids (42%) were the most commonly affected structures, followed by the cornea (35%) and iris (30%). Eyebrow madarosis was seen in 54% of patients. In the eyelids, ciliary madarosis (34%) and lagophthalmos (8%) were most commonly seen. Corneal involvement included corneal opacities (26%) and 8% patients had active keratitis, 15% had KPs on the endothelium, 11% had SPKs, 9% had vortex keratopathy, and 4% had thickened corneal nerves. 8% of 74 eyes had decreased corneal sensation. 11 eyes (15%) had active uveitis and 4 patients had bilateral uveitis at presentation. Iris atrophy was seen in 30% of eyes. Iris pearls were seen in 7% of eyes. Iris nodules and leproma were seen in only one patient. 19% of patients had dry eyes. Two patients with long-standing lepromatous leprosy had pupillary block glaucoma. 41% patients had grade 0 ocular disability, 27% had grade 1 ocular disability and 32% had grade 2 ocular disability.

BT - Leprosy Review DO - 10.47276/lr.96.3.2025069 IS - 3 LA - ENG M3 - Article N2 -

This cross-sectional descriptive study was carried out in the Department of Ophthalmology at Dr RPGMC Tanda Kangra (H.P.) over a one-year time period (2023). The total number of patients studied was 37 (74 eyes), including 16 new cases and 21 old cases.

The M:F ratio was 5:1. Most patients were in age groups 35–50 and >50 (43% each). The most common classification was lepromatous leprosy (51%), followed by borderline leprosy (30%); lepromatous cases had higher ocular disability than other groups.

65% of patients had ocular involvement related to leprosy. Eyelids (42%) were the most commonly affected structures, followed by the cornea (35%) and iris (30%). Eyebrow madarosis was seen in 54% of patients. In the eyelids, ciliary madarosis (34%) and lagophthalmos (8%) were most commonly seen. Corneal involvement included corneal opacities (26%) and 8% patients had active keratitis, 15% had KPs on the endothelium, 11% had SPKs, 9% had vortex keratopathy, and 4% had thickened corneal nerves. 8% of 74 eyes had decreased corneal sensation. 11 eyes (15%) had active uveitis and 4 patients had bilateral uveitis at presentation. Iris atrophy was seen in 30% of eyes. Iris pearls were seen in 7% of eyes. Iris nodules and leproma were seen in only one patient. 19% of patients had dry eyes. Two patients with long-standing lepromatous leprosy had pupillary block glaucoma. 41% patients had grade 0 ocular disability, 27% had grade 1 ocular disability and 32% had grade 2 ocular disability.

PB - Lepra PY - 2025 SP - 1 EP - 11 T2 - Leprosy Review TI - Ocular manifestations of leprosy in a tertiary health care centre in Northern India UR - https://leprosyreview.org/article/96/3/20-25069#:~:text=0-,Download,-A VL - 96 SN - 2162-8807 ER -