TY - JOUR
KW - BCG Vaccine
KW - Humans
KW - Immune Tolerance
KW - Immunotherapy
KW - leprosy
KW - Lymphocyte Activation
KW - Mycobacterium leprae
KW - Skin Tests
KW - T-Lymphocytes, Regulatory
AU - Rada E M
AU - Convit J
AU - Ulrich M
AU - Gallinotto M E
AU - Aranzazu N
AB - <p>Suppressor reactivity was studied in a group of leprosy patients before and after immunotherapy with a mixture of Mycobacterium leprae and BCG. The treatment increases the responses in lymphocyte transformation tests to levels which are comparable to those observed in BT-TT patients and reduces suppressor activity. The soluble extract of M. leprae appears to be more sensitive than purified intact bacilli in the lymphocyte transformation tests, but this preparation did not induce suppressor reactivity with the regularity observed when using a Dharmendra preparation.</p>
BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
C1 - http://www.ncbi.nlm.nih.gov/pubmed/2963084?dopt=Abstract
DA - 1987 Dec
IS - 4
J2 - Int. J. Lepr. Other Mycobact. Dis.
LA - eng
N2 - <p>Suppressor reactivity was studied in a group of leprosy patients before and after immunotherapy with a mixture of Mycobacterium leprae and BCG. The treatment increases the responses in lymphocyte transformation tests to levels which are comparable to those observed in BT-TT patients and reduces suppressor activity. The soluble extract of M. leprae appears to be more sensitive than purified intact bacilli in the lymphocyte transformation tests, but this preparation did not induce suppressor reactivity with the regularity observed when using a Dharmendra preparation.</p>
PY - 1987
SP - 646
EP - 50
T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
TI - Immunosuppression and cellular immunity reactions in leprosy patients treated with a mixture of Mycobacterium leprae and BCG.
VL - 55
SN - 0148-916X
ER -