TY - JOUR KW - Disability KW - Early detection KW - Immunology KW - Neglected disease KW - Pathology KW - leprosy AU - Serrano-Coll H AU - Restrepo-Rivera L AU - Cuadros-Urrego Y AU - Cardona-Castro N AB -

Leprosy is an infectious disease characterized by a broad immunological spectrum, which underlies its diverse clinical presentations and contributes to the physical and emotional disabilities experienced by patients with leprosy. Understanding the immunopathogenic mechanisms of this disease is essential for interpreting clinical manifestations and conventional diagnostic tests and developing diagnostic strategies for leprosy detection. This review aims to provide an overview of the immune response, clinical features and emerging diagnostic approaches in leprosy.

BT - Transactions of The Royal Society of Tropical Medicine and Hygiene DO - 10.1093/trstmh/traf058 LA - eng M3 - Research Article N2 -

Leprosy is an infectious disease characterized by a broad immunological spectrum, which underlies its diverse clinical presentations and contributes to the physical and emotional disabilities experienced by patients with leprosy. Understanding the immunopathogenic mechanisms of this disease is essential for interpreting clinical manifestations and conventional diagnostic tests and developing diagnostic strategies for leprosy detection. This review aims to provide an overview of the immune response, clinical features and emerging diagnostic approaches in leprosy.

PB - Oxford University Press (OUP) PY - 2025 T2 - Transactions of The Royal Society of Tropical Medicine and Hygiene TI - Decoding leprosy: immune response, clinical manifestations and emerging diagnostic approaches UR - https://watermark.silverchair.com/traf058.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA2swggNnBgkqhkiG9w0BBwagggNYMIIDVAIBADCCA00GCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMzi6dHHFtgxNFlWgkAgEQgIIDHrP3vKPkN02FPu0mWjD-B8ND_w7BBZV5QcqbL8nISmbqwfn SN - 0035-9203, 1878-3503 ER -