TY - JOUR KW - Dihydrolipoamide Dehydrogenase KW - Electron Transport Complex IV KW - Humans KW - leprosy KW - Macrophages KW - Peroxidases KW - Phagocytosis KW - Succinate Dehydrogenase AU - Maslov A K AU - Iushchenko A A AB -
Cytochrome oxidase (CCO), peroxidase, succinic dehydrogenase (SDG) and NADH-diaphorase were studied electron-cytochemically in leprous macrophages (LM) of granulomas of patients suffering from lepromatous leprosy. The LM peroxidase activity and location differed, this affecting the completeness of M. leprae phagocytosis. High CCO activity in LM cytoplasm was not a factor essentially influencing M. leprae disintegration. SDG and NADH-diaphorase, locating predominantly in membraneous structures of M. leprae, show low activity in LM cytoplasm.
BT - Arkhiv patologii C1 - http://www.ncbi.nlm.nih.gov/pubmed/2852935?dopt=Abstract DA - 1988 IS - 11 J2 - Arkh. Patol. LA - rus N2 -Cytochrome oxidase (CCO), peroxidase, succinic dehydrogenase (SDG) and NADH-diaphorase were studied electron-cytochemically in leprous macrophages (LM) of granulomas of patients suffering from lepromatous leprosy. The LM peroxidase activity and location differed, this affecting the completeness of M. leprae phagocytosis. High CCO activity in LM cytoplasm was not a factor essentially influencing M. leprae disintegration. SDG and NADH-diaphorase, locating predominantly in membraneous structures of M. leprae, show low activity in LM cytoplasm.
PY - 1988 SP - 51 EP - 4 T2 - Arkhiv patologii TI - [Evaluation of the functional state of the leprous macrophages]. VL - 50 SN - 0004-1955 ER -