A middle-aged male with lepromatous leprosy developed bouts of skin lesions of depigmented macules and patches of vitiligo, just following attacks of type II lepra reaction each time. In view of the present concept of autoimmunity playing a role in the pathogenesis of vitiligo as well as lepra reaction, their association in our patient appears to be more than fortuious. The depigmented macules persisted even after regression of skin lesions of leprosy following chemotherapy. The vitiligo macules responded partially to topical and systemic psoralen therapy.
BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/2703744?dopt=Abstract CN - Infolep Library - available DA - 1989 Jan IS - 1 J2 - Indian J Lepr LA - eng N2 -A middle-aged male with lepromatous leprosy developed bouts of skin lesions of depigmented macules and patches of vitiligo, just following attacks of type II lepra reaction each time. In view of the present concept of autoimmunity playing a role in the pathogenesis of vitiligo as well as lepra reaction, their association in our patient appears to be more than fortuious. The depigmented macules persisted even after regression of skin lesions of leprosy following chemotherapy. The vitiligo macules responded partially to topical and systemic psoralen therapy.
PY - 1989 SP - 44 EP - 8 T2 - Indian journal of leprosy TI - Vitiligo following type II lepra reaction. VL - 61 SN - 0254-9395 ER -