01643nas a2200349   4500000000100000008004100001260001300042653001900055653001900074653002000093653001200113653001500125653001600140653001800156653001200174653001000186653001600196653002500212653001200237653002500249653001700274653001100291100001200302700001800314700001700332245007500349856004100424300001100465490000700476520079600483022001401279       1989                            d  c1989 Sep10aAdrenal Cortex10aAdrenal Glands10aAdrenal Medulla10aAnimals10aArmadillos10aEndothelium10aKupffer Cells10aleprosy10aLiver10aMacrophages10aMicroscopy, Electron10aMuscles10aMycobacterium leprae10aPhagocytosis10aTongue1 aJob C K1 aMcCormick G T1 aHastings R C00aIntracellular parasitism of parenchymal cells by Mycobacterium leprae.  uhttp://ila.ilsl.br/pdfs/v57n3a10.pdf  a659-700 v573 a<p>The liver, skeletal muscle, and adrenal gland obtained from two nine-banded armadillos infected with Mycobacterium leprae were studied using an electron microscope. M. leprae were found in varying numbers inside hepatocytes, Kupffer's cells, striated muscle cells, adrenal cortical and adrenal medullary cells, endothelial cells, and macrophages. There was evidence to suggest that M. leprae were actively phagocytosed by the liver and skeletal muscle cells. The inert nature of M. leprae and its behavior as an almost ideal parasite of parenchymal cells are emphasized. The question of whether this unique parasitism of parenchymal cells and the possible processing and presentation of M. leprae antigens by these cells could be responsible for aberrant immune responses is raised.</p>
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