01724nas a2200313   4500000000100000008004100001260001300042653001500055653001000070653002100080653001100101653001100112653001000123653001300133653001200146653002400158653002500182653002500207653000900232653002500241100001500266245011500281856005900396300001000455490000700465050003200472520089200504022001401396       1989                            d  c1989 Sep10aAdolescent10aChild10aChild, Preschool10aFemale10aHumans10aIndia10aLepromin10aleprosy10aLeprosy, Borderline10aLeprosy, lepromatous10aLeprosy, Tuberculoid10aMale10aMycobacterium leprae1 aSehgal V N00aLeprosy in children: correlation of clinical, histopathological, bacteriological and immunological parameters.  uhttp://leprev.ilsl.br/pdfs/1989/v60n3/pdf/v60n3a05.pdf  a202-50 v60  aInfolep Library - available3 a<p>The study of leprosy in children has indicated an incidence of 10% amongst leprosy patients attending the clinic. The duration of the disease was usually less than 2 years. The expression of leprosy in this group was either a macule and/or a plaque. Classification was, therefore, different and conforms to indeterminate (I), borderline tuberculoid (BT) and borderline (BB) leprosy. Only occasionally were other clinical variants seen. The bacteriology was largely unproductive by slit-skin smears. The lepromin (Mitsuda) responses were positive in BT and unpredictable in BB patients. Epicutaneous responses to sensitization with dinitrochlorobenzene (DNCB) paralleled responses to lepromin. Microscopic pathology was of very little help. The correlation of these parameters was only 50-60% indicating that the diagnosis of leprosy should primarily be based on clinical features.</p>  a0305-7518