01577nas a2200337   4500000000100000008004100001260001300042653001000055653001000065653002800075653001100103653001100114653002900125653002800154653001200182653001600194653000900210653001300219653001700232100001700249700001200266700001500278700001500293700001500308700001400323245008500337300001000422490000700432520078600439022001401225       1992                            d  c1992 Jun10aAdult10aChild10aDiagnosis, Differential10aFemale10aHumans10aLeishmaniasis, Cutaneous10aLeishmaniasis, Visceral10aleprosy10aMacrophages10aMale10aNeuritis10aTime Factors1 aElhassan A M1 aAli M S1 aZijlstra E1 aEltoum I A1 aGhalib H W1 aAhmed H M00aPost-kala-azar dermal leishmaniasis in the Sudan: peripheral neural involvement.  a400-30 v313 a<p>Four patients developed post-kala-azar dermal leishmaniasis and neuritis (PKDL) 1 to 6 months following apparently successful treatment of kala-azar. The duration of the lesion varied between 1 month and nearly 5 years. The lesions were macules, papules, or nodules affecting the face, extremities, and trunk. The diagnosis was made by demonstration of the parasite in slit smear and biopsies and by a positive direct agglutination test (DAT). Histologically, the patients were found to have neuritis affecting the cutaneous nerves in the lesion only. The nerves showed a lymphohistiocytic infiltration and occasionally parasites. There was no impairment of sensation. Response to sodium stibogluconate was good. PKDL may simulate leprosy both clinically and pathologically.</p>  a0011-9059