01099nas a2200289   4500000000100000008004100001260001300042653001200055653001100067653002300078653001900101653003000120653002300150653001100173653001300184653001200197653002500209653003000234653003900264100001400303700001300317245012700330300001000457490000700467520032100474022001400795       1989                            d  c1989 Dec10aAnimals10aBiopsy10aBlotting, Southern10aDNA, Bacterial10aElectrophoresis, Agar Gel10aGene Amplification10aHumans10aKinetics10aleprosy10aMycobacterium leprae10apolymerase chain reaction10aRepetitive Sequences, Nucleic Acid1 aWoods S A1 aCole S T00aA rapid method for the detection of potentially viable Mycobacterium leprae in human biopsies: a novel application of PCR.  a305-90 v533 a<p>A simple procedure based on the polymerase chain reaction has been developed to detect Mycobacterium leprae, rapidly and unambiguously, in biological samples. Its application to small numbers of M. leprae cells (approximately 10(2] isolated from armadillo liver, mouse footpads or human biopsies is discussed.</p>  a0378-1097