02022nas a2200373   4500000000100000008004100001260001300042653001500055653001000070653000900080653002800089653001000117653002700127653002200154653001100176653001100187653002300198653001200221653000900233653001600242100001200258700001400270700001700284700001400301700001400315700001100329700001400340245003200354856005900386300000900445490000600454520117400460022001401634       1979                            d  c1979 Jun10aAdolescent10aAdult10aAged10aCarbohydrate Metabolism10aChild10aDiabetes Complications10aDiabetes Mellitus10aFemale10aHumans10aLeprostatic Agents10aleprosy10aMale10aMiddle Aged1 aNigam P1 aDayal S G1 aSrivastava P1 aJoshi L D1 aGoyal B M1 aDutt B1 aGupta M C00aDiabetic status in leprosy.  uhttp://www.ilsl.br/revista/detalhe_artigo.php?id=12365  a7-140 v43 a<p>The diabetic status of the local Jhansi patients (120 cases) was established before and after antileprosy treatment. Control studies were performed in normal healthy subjects (50 persons) without family history of diabetes mellitus. Random normals showed an incidence of diabetes only 2%, while leprosy patients (94 males and 26 females) had incidence of diabetic status of 14.2%. The highest incidence (19.3%) of diabetes was in lepromatous leprosy and lowest incidence (6.4%) in tuberculoid leprosy patients. Repeated studies in leprosy after treatment showed not only clinical improvement for leprosy but also disappearance of the chemical and latent diabetes mellitus and lowering of blood sugar levels in manifest diabetes mellitus. Incidentally it was noted that 'diabetic status' was worse among males (82.3%) and with advancing age. Association and improvement of diabetic status with specific treatment would tentatively suggest that Mycobacterium leprae lesions are not confined to skin alone but somehow also related to carbohydrate metabolism. A careful management of the chemical and latent diabetes may help in clinical management of leprosy too.</p>
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