01158nas a2200253   4500000000100000008004100001260001300042653001200055653001600067653002300083653001200106653000900118653002500127653001700152100001400169700001300183700001300196700001600209245006400225300001000289490000700299520058400306022001400890       1989                            d  c1989 Feb10aAnimals10aBCG Vaccine10aBacterial Vaccines10aleprosy10aMice10aMycobacterium leprae10aTuberculosis1 aSingh N B1 aLowe A C1 aRees R J1 aColston M J00aVaccination of mice against Mycobacterium leprae infection.  a653-50 v573 a<p>Intradermal immunization with killed Mycobacterium leprae renders mice immune to infection with viable M. leprae. This protection is long lasting and systemic in that immunization in the left flank results in protection in both the left and right footpads. Immunization with Mycobacterium vaccae was ineffective in protecting mice against M. leprae infection, while Mycobacterium bovis BCG provided partial protection. Mycobacterium habana TMC 5135 (now known as Mycobacterium simiae) was found to be as effective as M. leprae in protecting mice against footpad infection.</p>  a0019-9567