01590nas a2200361   4500000000100000008004100001260001700042653001500059653001000074653002500084653002100109653001100130653001100141653002400152653002500176653000900201653001600210653001000226653002100236653002700257653001600284653001400300653002100314100001400335700001400349700001700363245006000380856007500440300001000515490000600525520068300531022001401214       2001                            d  c2001 Jan-Mar10aAdolescent10aAdult10aCase-Control Studies10aEndemic Diseases10aFemale10aHumans10aLeprosy, Borderline10aLeprosy, lepromatous10aMale10aMiddle Aged10aSudan10aThyroid Diseases10aThyroid Function Tests10aThyrotropin10aThyroxine10aTriiodothyronine1 aKheir M M1 aAhmed A M1 aElsarrag A A00aThyroid functional status in leprosy patients in Sudan.  uhttp://applications.emro.who.int/emhj/0701_2/2001_7_1-2_79_83.pdf?ua=1  a79-830 v73 a<p>We studied 45 adult patients with untreated lepromatous leprosy and borderline leprosy, presenting at clinics in Khartoum and Omdurman, to assess clinical and biochemical effects of the disease on thyroid function. A matching control group of 30 subjects, without symptoms or signs of thyroid disease, were included for comparison. Thyroxine, triiodothyronine and thyrotrophin levels were within normal range. Mean serum thyroxine was low in both groups (significant in lepromatous leprosy patients only). Mean serum triiodothyronine was high in both groups (significant in neither group). Mean thyrotrophin was significantly higher in both groups compared with controls.</p>  a1020-3397