02646nas a2200265 4500000000100000008004100001260001200042653001200054653001700066653001500083653003400098653002200132100001400154700001400168700001300182700001400195700001300209700001100222245015400233856007900387300001300466490000700479520188000486022001402366 2023 d c01/202310aLeprosy10aEpidemiology10aIncidence.10aDegree of Physical Disability10aTime Series Study1 aMoreira R1 aBezerra J1 aSantos F1 aPascoal L1 aSantos L1 aNeto M00aClinical-epidemiological characteristics and temporal trend of new cases of grade 2 disability leprosy in the state of Maranhão, Brazil, 2011- 2020. uhttps://www.scielo.br/j/ress/a/jV7HHvfBrF6JSVYdPS5QnrN/?format=pdf&lang=en ae20224350 v323 a
Main Results: Out of 2,147 grade 2 disability leprosy cases, the majority were male, of mixed race/skin color, multibacillary and borderline. The São Luís regional health unit showed a falling trend.
Implications for Services: The results can guide strategies for the leprosy control program in the state, aiming at new approaches towards early diagnosis, treatment and prevention of disabilities.
Perspectives: Further studies are needed, such as spatial distribution of cases and detection rates of leprosy in children under 15 years of age, in order to gain a better understanding of the epidemiological profile of leprosy in Maranhão.
Objective: to describe the clinical and epidemiological characteristics of new cases of grade 2 disability leprosy and to analyze its trend in the state of Maranhão, from 2011 to 2020.
Methods: this was a descriptive cross-sectional and ecological time-series study, using data from the Notifiable Health Conditions Information System. A descriptive analysis of the event was carried out according to the sociodemographic and clinical-laboratory characteristics of the cases. The temporal trend of event incidence was analyzed using Prais-Winsten regression.
Results: of the 2,147 cases, 71.5% were male, 48.9% had up to 8 years of schooling, 66.5% were of mixed race/color, 95.5% had the multibacillary form, 58.8% were borderline, 32.3% had negative bacilloscopy at diagnosis. There was a stationary trend in the state and a falling trend in the São Luís Health Region (annual percentage change = -64.4%; 95% confidence interval: -73.7;-51.9).
Conclusion: incidence trend was stable in the state of Maranhão and falling in São Luís.
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