01102nas a2200265   4500000000100000008004100001260001300042653002700055653002400082653003100106653001600137653002500153653001100178653001200189653002500201100001600226700001400242700001500256245011100271300001100382490000700393050003200400520039000432022001400822       1989                            d  c1989 Oct10aAntibodies, Monoclonal10aAntigens, Bacterial10aCell Transformation, Viral10aGlycolipids10aHerpesvirus 4, Human10aHumans10aleprosy10aMycobacterium leprae1 aMoudgil K D1 aGupta S K1 aTalwar G P00aGeneration and characterization of a human monoclonal antibody against phenolic glycolipid-I of M. leprae.  a479-840 v61  aInfolep Library - available3 a<p>The development of an Epstein-Barr virus transformed human B-cell line secreting a monoclonal antibody (MoAb), KR2/B5 is described. KR2/B5 is an IgM type of antibody and is highly specific for phenolic glycolipid-I (PGL-I) a component unique to M. leprae. The MoAb appears to be directed against the terminal sugar residue of the immunodominant trisaccharide component of PGL-I.</p>  a0254-9395