02090nas a2200229 4500000000100000008004100001260003000042653003200072653003500104653000800139653000800147653002200155653001500177100001500192700001900207700001300226245009000239856008800329300001200417490000700429520142400436 2023 d b Hind Kusht Nivaran Sangh10aModified Rankin Scale (mRS)10aLeprosy Neuropathy Scale (LNS)10aWHO10aMDT10aAcid fast bacilli10aDisability1 aMisra U. K1 aChaudhary S. K1 aKalita J00aMonitoring the Outcome of Leprosy Using Leprosy Neuropathy Scale: A Preliminary Study uhttps://www.ijl.org.in/published-articles/29062023223823/3-UK-Misra-et-al-Final.pdf a111-1190 v953 a
The disability and progress of leprosy patients is monitored by the WHO disability grading system which has limited sensitivity in leprous neuropathy. This study aims to report the spectrum of leprosy patients at a tertiary care neurology service and compare WHO grading, modified Rankin Scale (mRS) and Leprosy Neuropathy Scale (LNS) in monitoring the treatment outcome. The patients with leprosy diagnosed as per WHO criteria were subjected to medical history and clinical examination. Their disability was graded as per WHO grading scale, modified Rankin scale (mRS) and LNS. These parameters were repeated and compared after six months of multiple drug therapy (MDT). Thirty-eight patients with leprosy, aged 40 (`5-80) years, 33 of whom were males have been evaluated. The duration of symptoms was 24 (91-120) months. Mononeuropathy was present in 14, mononeuropathy multiplex in 24, trophic ulcer in two, claw hand in 11, wrist drop in two, foot drop in four, facial palsy in one, Charcot’s joint in one and lepra reaction in seven patients. Their disability as per WHO grade 1 and 2 was in 19 patients each. After 6 months of MDT, WHO grade improved in two patients, mRS revealed improvement in seven and LNS in nine patients. LNS- a clinical scale, seems more effective and easier to use for monitoring the progress/ outcome of neuropathy in leprosy patients and may complement the WHO grading scale.