01674nas a2200229   4500000000100000008004100001260004400042653002100086653002500107653002200132653002000154653003400174100001900208700000900227700001800236700001100254700001200265245007400277856011600351520096300467022001401430       2023                            d  bSpringer Science and Business Media LLC10aGeneral Medicine10aMycobacterium leprae10aReversal reaction10aType 1 reaction10aunilateral facial nerve palsy1 aHarikrishna GV1 aCA J1 aDoddapaneni S1 aBhat N1 aBhanu P00aA Case of Borderline Tuberculoid Leprosy With Type One Lepra Reaction  uhttps://www.cureus.com/articles/151461-a-case-of-borderline-tuberculoid-leprosy-with-type-one-lepra-reaction#!/3 a<p>Leprosy is a chronic infectious disease caused by&nbsp;<em>Mycobacterium leprae</em>, which primarily affects the skin and peripheral nerves. The variants that can be identified include tuberculoid (TT), borderline tuberculoid (BT), mid-borderline (BB), borderline lepromatous (BL), and lepromatous forms (LL). Type one lepra reactions are delayed hypersensitivity reactions that are often observed in borderline variants due to an unstable immunological response. They can exacerbate skin lesions and neuritis, leading to a higher risk of disabilities and deformities. Early detection and management would play a major role in limiting morbidity. Here, we present a case of a 46-year-old male diagnosed with borderline tuberculoid leprosy on multidrug therapy who developed features suggestive of type one lepra reaction. Early recognition of this entity helps in mitigating the risk of permanent nerve damage, disability, deformity, and morbidity.</p>
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