01608nas a2200169   4500000000100000008004100001100001800042700001400060700002000074700002400094700001400118245009700132856007600229300001400305490000600319520111300325       2023                            d1 aPurnamasari R1 aMuniroh M1 aKusumaningrum N1 aMundhofir F. E. P. 1 aYuniati R00aEffect of Clitoria Ternatea as Adjuvant Therapy on Serum Cortisol Levels in Leprosy Reaction  uhttps://aisyah.journalpress.id/index.php/jika/article/download/8134/pdf  a237–2420 v83 a<p>This study was to investigate the effect of using an extract from&nbsp;<em>Clitoria ternatea</em>&nbsp;as adjuvant therapy on the levels of blood cortisol in patient with leprosy reaction. The current investigation is an experimental study designed a single-blind randomized controlled trial comparison between two groups. The control group which received standard prednisolone therapy and the intervention group received standard prednisolone therapy and adjuvant therapy of&nbsp;<em>Clitoria ternatea</em>&nbsp;extract dose 2 g/day for one month. Serum levels of cortisol were measured by ELISA. The average serum level of cortisol decrease in control grup with statistically significant (p=0.008). The average serum level of cortisol increase in treatment grup with statistically significant (p=0.026) similar with average difference of both groups (p=0.02). According to the results of the study, the use of an extract from&nbsp;<em>Clitoria ternatea</em>&nbsp;extract 2 g / day for one month as adjuvant therapy significantly increase the serum cortisol levels in patients with leprosy reaction</p>