02100nas a2200229 4500000000100000008004100001260001200042100001400054700001400068700001500082700001200097700001600109700001700125700001400142700001500156245004600171856010400217300001400321490000700335520151400342022001401856 2022 d c12/20221 aMartins P1 aPaixão A1 aMesquita M1 aSilva N1 aQuintella L1 aGonçalves M1 aFreitas A1 aFerreira C00aLucio phenomenon in an adolescent female. uhttps://www.hmpgloballearningnetwork.com/site/wounds/case-report/lucio-phenomenon-adolescent-female aE147-E1510 v343 a

INTRODUCTION: LP is an uncommon reaction characterized by outbreaks of erythematous, painful, slightly infiltrated macules and hemorrhagic bullae that progress to ulceration that occurs in patients with Lucio leprosy and lepromatous leprosy; it can be considered a variant of type 2 or 3 reaction. Death can occur because of blood dyscrasia or sepsis. Precipitating factors include infections, drugs, and pregnancy.

CASE REPORT: A 17-year-old female presented with fever, tachycardia, adynamia, extensive hyperchromic and purplish macular lesions, erythematous plaques, multiple blisters with serohematic content, and necrotic exulcerations and ulcers on the lower and upper limbs, ears, nose, palms, and soles. Past medical history included leprosy and a first trimester miscarriage. The patient was diagnosed with borderline lepromatous leprosy in reactional state (ie, LP) and MDT was restarted in association with systemic corticosteroid and pentoxifylline. Local therapy was performed with cleansing solution (0.9% sodium chloride), dressing with silver sulfadiazine ointment, and surgical debridement of the necrotic lesions.

CONCLUSION: LP is a rare manifestation that may be fatal because of considerable inflammatory activity and the extent and severity of dermatologic lesions. Pregnancy is strongly associated with exacerbation of symptoms. Debridement is required to excise nonviable tissue and promote wound healing.

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