01118nas a2200145   4500000000100000008004100001100001900042700001600061700001400077700001400091245011100105856006100216490000700277520068800284       2021                            d1 aRusmawardiana 1 aArgentina F1 aPamudji R1 aFantoni O00aReversal reaction in a borderline lepromatous leprosy patient after COVID-19 vaccine: Prevention or risks?  uhttp://jpad.com.pk/index.php/jpad/article/view/1953/18090 v323 a<p>Reversal reaction in leprosy is an immunologically mediated response due to alteration of cell-mediated immunity associated in leprosy spectrum. In COVID-19 pandemic era, leprosy patient is susceptible to the infection. According to guideline, vaccination should be given to leprosy patients. This case reported a 33-year-old male with reversal reaction after COVID-19 vaccination. On examination, patient had erythematous plaque of the face, trunk and extremities, also multiple ulcers of the trunk and extremities. Treatment was commenced immediately with prednisone and second vaccination was delayed. Within our follow-up, marked improvement were obtained after 6 weeks.</p>