01620nas a2200289   4500000000100000008004100001260001200042653001600054653001600070653002800086653002400114653001500138100001400153700001500167700001600182700001300198700001500211700001400226700001200240700001400252245009800266856008100364300001100445490000700456520085300463022001401316       2022                            d  c01/202210aBone Marrow10aCase report10aFever of Unknown Origin10alepromatous leprosy10aNeuropathy1 aSantana M1 ada Costa W1 aCelestino I1 aSantos D1 aDornelas B1 aPavelka M1 aLuppi A1 aGoulart I00aFever of Unknown Origin, Wasting Syndrome and Bone Marrow Involvement: A Leprosy Case Report.  uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300819/pdf/fimmu-13-916319.pdf  a9163190 v133 a<p>, the etiologic agent of leprosy, is an acid-fast-staining and slow-growing bacilli that infect macrophages and Schwann cells individually or through forming globi. The clinical presentation of leprosy is broad and depends on the host immune response. We report a case of a 42-year-old Brazilian man presenting with fever of unknown origin (FUO), anemia, wasting syndrome, and neuropathy. The diagnosis of lepromatous leprosy was made after an extensive investigation revealed the presence of in the bone marrow. Bone marrow involvement in leprosy is rare and some authors believe the presence of in the bone marrow can act as a reservoir of the disease facilitating future relapses. It is important to investigate bone marrow involvement in leprosy, especially when the patient presents with cytopenias and positive epidemiologic history.</p>
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