01952nas a2200169   4500000000100000008004100001100001600042700001800058700001700076700001500093700001500108700001700123245011000140300001200250490000700262520151300269       2022                            d1 aGarcía YGM1 aFernández BM1 aMouriño CNA1 aCabrera MM1 aGuerra YNP1 aGonzález SG00aDengue como enfermedad asociada causante de debut de lepra en estado reaccional. Presentación de un caso  a187-1950 v333 a<p>Leprosy is a slowly developing disease, which can present acute episodes known as reactional states or leprosy reactions that require the patient to seek medical attention. A 34-year-old female patient, with general malaise, consisting of fever of 38 and 39oC, intense joint pain, headache and body injuries described as hives on neck, chest and arms, also inflammation on face, hands and feet and inability to walk due to intense joint and muscle pain comes for medical attention The dermatological examination revealed a generalized, polymorphous skin picture, consisting of erythematous, infiltrated plaques of variable sizes that converge to form large plaques with well-defined edges over 20 twenty in number and diameters ranging from 3 to 6 cm, some with a central area of normal skin, distributed over the body respecting the palms of the hands and the soles of the feet. There is also infiltration of the ears and hands and feet with edema. The final diagnosis was the debut of lepromatous Borderline Leprosy in reactionary state caused by Dengue. It is concluded that with regard to infectious diseases, the defect of the immunological system of those affected by leprosy, especially during the course of reactional states, plays an important role since it makes them more susceptible to other infections. Paradoxically, these entities are the cause of reactional states in many cases, by generating a vicious circle that makes it difficult to establish a direct relationship between them.</p>