01019nas a2200145   4500000000100000008004100001260003800042100001200080700001400092700001100106245003400117300001200151520069200163020001800855       2022                            d  bSpringer International Publishing1 aNunzi E1 aMassone C1 aNoto S00aDiagnostic Work-Up of Leprosy  a291-2993 a<p>Leprosy services are organized on two levels: the basic level integrated into general health services and a second, referral level. In most cases, leprosy has slow onset, in the skin. The first elements to be considered for diagnosis are the arrangement and characteristics of the lesions. After this clinical analysis, paraclinical tests are performed (testing for anesthesia and slit-skin smear examination for acid-fast bacilli by direct microscopy). Histopathology is the gold standard in leprosy diagnosis. Diagnosis is based on clinical, microbiological, and histopathological parameters. The diagnostic work-up is completed by searching for peripheral nerve trunk damage.</p>
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