01282nas a2200217 4500000000100000008004100001260001200042653006400054653002500118653001800143653008100161100001300242700001300255700001200268700001300280700001400293245008300307300002000390520064000410022001401050 2022 d c01/202210aHansen's disease Apart from proper footwear for prevention10aPlatelet rich fibrin10aTrophic ulcer10aone simple and elegant intervention involves the use of platelet rich fibrin1 aDorjay K1 aTandon S1 aSingh A1 aSharma S1 aSardana K00aPlatelet rich fibrin: A novel treatment for trophic ulcer in Hansen's disease. a4947552110694403 a

Patients with Hansen's disease are liable to develop non-healing trophic ulcers. The aim of this study was to determine the efficacy of autologous platelet rich fibrin (PRF) applied at weekly intervals in the management of trophic ulcers. The mean age of the patients, duration and size of ulcer were 44.3 years, 7.4 months and 6.25cm respectively. After the third sessions of weekly dressing, there was a significant reduction in the ulcer area (p value  =  0.015). All ulcers healed by a maximum of six weeks. No adverse events were noted. PRF thus seems a feasible, safe, simple and cost-effective treatment method.

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