01690nas a2200217   4500000000100000008004100001260001200042653012500054100001500179700001000194700001200204700001200216700001200228700001300240245005700253856004200310300001400352490000700366520108500373022001401458       2021                            d  c10/202110a Leprosy, Lepra reactions, Type 1 reversal reactions, Erythema nodosum leprosum, ENL, Peripheral neuropathy, Neuritis. 
1 aTabassum S1 aZia M1 aKhoja A1 aDavid J1 aIqbal M1 aJunaid M00aLepra reactions: A study of 130 cases from Pakistan.  uhttps://jpma.org.pk/PdfDownload/10883  a2317-23200 v713 a<p><strong>Objective: </strong>To determine the occurrence and characteristics of lepra reactions in leprosy patients.</p>

<p><strong>METHODS: </strong>The retrospective study was conducted at the Marie Adelaide Leprosy Centre, Karachi, and comprised data of patients admitted between January 1, 2013, and December 31, 2015, for the management of lepra reactions. Data was noted on a detailed proforma and was analysed using Microsoft Excel and applying chi-square test.</p>

<p><strong>RESULTS: </strong>Of the 130 cases, 95(73%) were males and 35(27%) were females. Mean age at onset of the first episode was 39±14 years. Borderline lepromatous was the most common classification 76(58%), with 40(53%) of them having type 1 reaction as the first episode and 36(47%) having a type 2 reaction Risk factors associated with recurrence were skin lesions, fever, lymphadenopathy and type of reaction (p&lt;0.05).</p>

<p><strong>Conclusion: </strong>Healthcare providers need to be aware of the clinical manifestations of lepra reactions in order to diagnose them early.</p>
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