01417nas a2200229 4500000000100000008004100001260006000042653004100102653003400143100001400177700001500191700001500206700001400221700001200235700001400247245009000261856012600351300001200477490000600489520067800495022001401173 2021 d bPublicacoes Cientificas de Acesso Aberto e Editora LTDA10aGeneral Earth and Planetary Sciences10aGeneral Environmental Science1 aPitta IJR1 aMietto BDS1 aCamilo ADS1 aAntunes S1 aSarno E1 aJardim MR00aClinical, Neurophysiological and Histopatological correlations in Pure Neural Leprosy uhttps://bjcasereports.com.br/index.php/bjcr/article/view/clinical_neurophysiological_and_histopathological_correlations_i a105-1130 v13 a
Although neuropathy remains one of the most problematic issues faced by leprosy patients, the evolving process of its findings continues a challenge particularly in pure neural leprosy (PNL). We evaluated neurological examination, nerve conduction studies and histhopathological data of patients with PNL and ulnar neuropathy. Patients with longer duration of symptoms had reduction in the motor conduction velocities and patients with fibrosis in the biopsy had axonal damage in the nerve conduction studies. This suggests that focal demyelination may be present in leprosy patients at the moment of the diagnosis and be related to the duration of the neuropathy.
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