01286nas a2200337 4500000000100000008004100001260001700042653001500059653001000074653000900084653001600093653002000109653000800129653001100137653001100148653001200159653000900171653001600180653002500196100001100221700001000232700001200242700001100254700001500265245006000280300001000340490000700350050003200357520054500389022001400934 1990 d c1990 Jan-Mar10aAdolescent10aAdult10aAged10aClofazimine10aCrystallization10aEye10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aPigments, Biological1 aKaur I1 aRam J1 aKumar B1 aKaur S1 aSharma V K00aEffect of clofazimine on eye in multibacillary leprosy. a87-900 v62 aInfolep Library - available3 a
Seventy-six patients of multibacillary leprosy received clofazimine as part of multidrug therapy (MDT) for periods ranging between 6 and 24 months. Complete ocular examination including slit lamp microscopy and examination of tears was carried out in all these patients. Reddish brown conjunctival and corneal pigmentation was seen in 46% and 53% of the patients respectively. Clofazimine crystals in tears were found in 32% of the patients. Apart from this no other eye changes or symptoms attributable to clofazimine were observed.
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