01539nas a2200337   4500000000100000008004100001260001300042653002900055653002500084653001600109653001100125653002500136653000900161653001200170653002300182653002500205653001200230653001000242653002600252100001500278700001400293700001700307700001500324700001500339245006700354856004100421300001000462490000700472520070800479022001401187       1990                            d  c1990 Mar10aAutonomic Nervous System10aCase-Control Studies10aHomeostasis10aHumans10aIntraocular Pressure10aIris10aleprosy10aNerve Degeneration10aP-Hydroxyamphetamine10aPosture10aPupil10aRetrospective Studies1 aLewallen S1 aHussein N1 aCourtright P1 aOstler H B1 aGelber R H00aIntraocular pressure and iris denervation in Hansen's disease.  uhttp://ila.ilsl.br/pdfs/v58n1a06.pdf  a39-430 v583 a<p>We retrospectively analyzed 255 Hansen's disease patients and found low intraocular pressure (less than 7 mm Hg) in 12% of them. We showed a correlation between low intraocular pressure and avascular keratitis and iritis. We also found that patients with low intraocular pressures had abnormally large postural changes in intraocular pressure. We speculate that abnormalities in the autonomic innervation of the anterior segment of the eye may be related to the intraocular pressure abnormalities. Further investigations along this line may increase our understanding not only of the pathophysiology of Hansen's disease but also of the mechanisms regulating homeostasis of intraocular pressure.</p>
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