01449nas a2200181   4500000000100000008004100001260001200042100001300054700001400067700001400081700001400095245008400109856008100193300000800274490000700282520096400289022001401253       2021                            d  c01/20211 aMaciel L1 aFrança L1 ade Deus B1 aFormiga C00aAcute pancreatitis associated with multibacillary polychemotherapy for leprosy.  uhttps://www.scielo.br/j/rimtsp/a/ncF9bYfwbpBmV5fNkXqs4kc/?format=pdf&lang=en  ae730 v633 a<p>Acute pancreatitis (AP) is an inflammatory disease associated with abdominal pain and elevated serum pancreatic enzymes. The most common etiologies are gallstones and alcoholism. Drug-induced AP is quite rare, lacks a solid understanding and has been occasionally reported. The diagnosis requires a great suspicion and a careful exclusion of other causes. We present a case of a 37-year-old man, previously diagnosed with leprosy that developed acute pancreatitis after starting the multibacillary polychemotherapy (PCT/MB). After a month of treatment and the discontinuation of the PCT/MB, the therapy was restarted and a new episode of AP occurred. Three months after this last episode, the PCT/MB was reintroduced, changing one of the medications and the patient had no recurrence of AP or other reactions. Therefore, it is important to take into account that there is a risk of acute pancreatitis in patients on multidrug therapy (MDT) for leprosy.</p>  a1678-9946