01060nas a2200169   4500000000100000008004100001260001600042653001600058100001600074700001700090700001700107700001500124245004800139856007200187520061700259022001400876       2021                            d  bElsevier BV10aDermatology1 aFernandes T1 ade Andrade V1 aNascimento I1 aMatias AKS00aHistoid leprosy presenting as a large tumor  uhttps://www.sciencedirect.com/science/article/pii/S03650596210021053 aHistoid leprosy is a rare form of multibacillary leprosy, characterized by the presence of papules, plaques, or nodules whose appearance is keloid-like, skin colored, or erythematous. Fusiform cells are the main histopathological feature. Due to the fact that it can simulate other dermatological lesions, for example, dermatofibroma and neurofibroma, it constitutes a diagnostic challenge for clinicians and pathologists. It is a bacilliferous form of leprosy, and it plays an important role in disease transmission. A case of a patient with histoid leprosy living in the Northeast Region of Brazil is reported.  a0365-0596