01819nas a2200205   4500000000100000008004100001260001200042653003100054653002400085100001300109700001400122700001700136700002100153245010200174856007800276300001400354490000700368520122400375022001401599       2021                            d  c01/202110aActivities of Daily Living10aActivity limitation1 aAmaral L1 aFelippe L1 aGonçalves G1 aChristofoletti G00aActivity limitations in leprosy and their association to cognition and neuropsychiatric symptoms.  uhttps://www.scielo.br/pdf/reben/v74n1/0034-7167-reben-74-01-e20200649.pdf  ae202006490 v743 a<p><b>OBJECTIVES: </b>to analyze activity limitations in patients with leprosy and their association to cognition and neuropsychiatric symptoms.</p><p><b>METHODS: </b>this cross-sectional design study included sixty patients with multibacillary leprosy assisted at a reference center. Participants were divided according to their physical disability and submitted to instruments assessing daily activities (basic and instrumental), cognitive functions, and neuropsychiatric symptoms. The order of the instruments was random to avoid any interference of test sequence on the results.</p><p><b>RESULTS: </b>fifty-five percent of the participants presented physical disabilities. All patients were independent in performing basic activities but sixty-six percent presented difficulties in performing instrumental activities. Cognitive decline and neuropsychiatric symptoms were seen in advanced stages of the disease, but they were more associated to patient age than to leprosy.</p><p><b>CONCLUSIONS: </b>leprosy patients presented physical disabilities and difficulties in performing instrumental daily activities. Cognitive decline and neuropsychiatric symptoms were more associated to aging than to leprosy itself.</p>  a1984-0446