01053nas a2200193 4500000000100000008004100001260001200042653002000054653003300074653001800107100001400125700001500139700001600154700001600170700001400186245013100200520051400331022001400845 2021 d c02/202110aHistoid leprosy10aMycobacterium indicus pranii10aRecurrent ENL1 aKothari R1 aVashisht D1 aPudasaini N1 aVenugopal R1 aPaliwal G00aRecurrent Erythema Nodosum Leprosum Associated With Mycobacterium Indicus Pranii Vaccine In A Case Of Leprosy: A Rare paradox.3 a

Erythema nodosum leprosum (ENL) is the commonest manifestation of type 2 lepra reaction (T2LR) due to immune complex mediated inflammation in patients of lepromatous (LL) and borderline lepromatous (BL) leprosy. Vaccines given as immunotherapy in leprosy may expedite early smear negativity and may hasten complete recovery. However, vaccination can also be associated with reactions. Majority of vaccine induced lepra reactions were reported about five decades back in the era of smallpox vaccination.

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