01520nas a2200169   4500000000100000008004100001260001200042100001200054700001300066700001200079700001500091700001400106245007000120856012600190520102000316022001401336       2021                            d  c02/20211 aDabas G1 aNarang T1 aDogra S1 aAggarwal D1 aRadotra B00aPalmoplantar Involvement in Leprosy: A Clinicopathological Study.  uhttps://www.ajtmh.org/view/journals/tpmd/aop/article-10.4269-ajtmh.19-0598/article-10.4269-ajtmh.19-0598.xml?tab_body=pdf3 a<p>Palmoplantar involvement has been infrequently reported in leprosy and is an easily misdiagnosed entity. The institutional database of leprosy clinic from 2015 to 2018 was accessed. Details pertaining to demography, clinical presentation, comorbidities (if any), treatment received, and outcome were analyzed in leprosy patients with palmoplantar involvement. Among the 520 patients studied, the involvement of palms and/or soles was reported in 49 (9.4%) patients. Isolated palm involvement was the most frequent (26/49, 53.1%), followed by both palm and sole involvement (12/49, 24.5%) and sole involvement alone (11/49, 22.4%). A higher incidence of lepra reactions and disabilities was noted in patients with palmoplantar involvement than in those without (P < 0.0001). Palmoplantar involvement in leprosy, although uncommon, is associated with a higher risk of reactions and disabilities. A knowledge of this end of the spectrum can help in maintaining a high index of suspicion and reduce misdiagnosis.</p>  a1476-1645