02024nas a2200433 4500000000100000008004100001260000900042653001500051653001000066653001600076653000900092653002200101653002400123653001100147653001000158653002100168653002800189653001100217653001100228653001100239653001100250653001200261653000900273653001600282653002500298653001700323653003000340653001600370653001600386100001600402700002000418700002200438700001600460245009100476300000900567490001500576520098500591022001401576 2008 d c200810aAdolescent10aAdult10aAge Factors10aAged10aAged, 80 and over10aAntigens, Bacterial10aBrazil10aChild10aChild, Preschool10aCross-Sectional Studies10aFamily10aFemale10aHumans10aInfant10aleprosy10aMale10aMiddle Aged10aMycobacterium leprae10aRisk Factors10aSeroepidemiologic Studies10aSex Factors10aYoung Adult1 aAndrade ARC1 aFaria Grossi MA1 aBührer-Sékula S1 aAntunes CMF00aSeroprevalence of ML Flow test in leprosy contacts from State of Minas Gerais, Brazil. a56-90 v41 Suppl 23 a

Leprosy is a public health problem in Brazil. Epidemiological control actions are based on the diagnosis and treatment of leprosy patients and household contact surveillance. Serological tests for leprosy could identify from among the contacts those at greater risk of developing leprosy in the future. ML Flow was administered to 2,840 household contacts of new leprosy cases diagnosed from October 2002 to March 2004, in State of Minas Gerais. ML Flow was positive in 20.5% of leprosy contacts, with high seropositivity among males (22.4%), individuals aged over 15 years-old (21.7%) and individuals in contact with multibacillary cases (23.9%). The chances of a household contact presenting a seropositive test was related to household contact with a multibacillary index case (OR=1.75), age over 15 years-old (OR=1.38) and male gender (OR=1.25). Follow-up of these contacts is necessary to evaluate the real role of seropositivity in the development of leprosy disease.

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