01480nas a2200289 4500000000100000008004100001260001300042653001200055653002000067653002700087653001100114653002500125653001200150653001900162653000900181653001200190100001400202700001300216700001500229700001100244700001400255245016900269300001000438490000700448520072100455022001401176 1990 d c1990 Nov10aAnimals10aCercopithecidae10aCercopithecus aethiops10aFemale10aIntraocular Pressure10aleprosy10aMacaca mulatta10aMale10aPosture1 aHussein N1 aOstler B1 aGormus B J1 aWolf R1 aWalsh G P00aIntraocular pressure changes and postural changes of intraocular pressure in experimentally induced Hansen's disease of rhesus, mangabey, and African green monkeys. a647-90 v743 a
In our long term evaluation of patients with Hansen's disease we have frequently found reduction of their intraocular pressure. Furthermore, we noted changes in their intraocular pressure on change of posture. To determine if these changes have any significance we measured the intraocular pressures of 24 experimentally infected and 39 control monkeys in both sitting and reclining positions. We found significant reduction of intraocular pressure in 66.7% compared with controls in the sitting position, and a significant increase in intraocular pressure in 79% when checked first in the sitting then in the reclining position. We offer a possible pathophysiological explanation as to why the changes occur.
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