01163nas a2200181   4500000000100000008004100001260001200042100001300054700001500067700002400082700001500106700001400121245010100135856004600236490000700282520067800289022001400967       2020                            d  c09/20201 aRobati R1 aMozafari N1 aBidari-Zerehpoosh F1 aNiknejad N1 aBizaval Z00aLepromatous leprosy presenting with type II reaction before and type I reaction after treatment.  uhttps://escholarship.org/uc/item/1f76n0b40 v263 a<p>Lepromatous leprosy is associated with a high bacillary load and poor cellular immune response. Early dermatologic manifestations include erythematous macules, papules, nodules, and plaques with a symmetrical distribution. Leprosy also shows two major reaction states including type I (reversal reaction) and type II (vasculitis). These reactions are usually seen in some patients who are undergoing treatment. Herein, we report an interesting patient with lepromatous leprosy who presented with skin lesions of type II reaction without receiving any anti-leprosy treatment and surprisingly showed a type I reaction eight months after the beginning of the treatment.</p>  a1087-2108