01163nas a2200193 4500000000100000008004100001260000900042653001100051653001200062653002700074653002800101100001500129700001700144700001600161245009800177300000900275520067100284022001400955 1990 d c199010aHumans10aleprosy10aPeptidyl-Dipeptidase A10aTuberculosis, Pulmonary1 aVinnik L A1 aGerovich L M1 aBalybin E S00a[Angiotensin converting enzyme in the blood serum of patients with tuberculosis and leprosy]. a54-63 a

Angiotensin-converting enzyme (ACE) levels in the serum of 15 patients with pulmonary tuberculosis and 9 with leprosy were measured by means of a spectrophotometric method. The serum produced from 10 blood donors was used as a control. Leprosy is accompanied by a sharp drop of ACE levels, which is attributed by the authors to a cellular immunodeficiency. In case of tuberculosis, a higher ACE level in blood often follows fibrosis formed in the lung along with a tuberculin hyperergia. The opinion that the ACE level reflects the tuberculosis or leprosy activity as well as the granulomatous tissue extension in tuberculosis patients has not been confirmed.

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