01964nas a2200445 4500000000100000008004100001260000900042653001500051653001000066653001100076653000900087653002800096653001100124653001900135653001900154653001000173653001000183653001100193653001200204653000900216653001600225653001500241653001700256653001000273100001500283700001400298700001400312700002200326700001200348700001200360700001300372700001200385700001400397700001200411245009200423300001200515490000600527520097100533022001401504 1990 d c199010aAdolescent10aAdult10aAfrica10aAged10aChi-Square Distribution10aFemale10aHIV Antibodies10aHIV Infections10aHIV-110aHIV-210aHumans10aleprosy10aMale10aMiddle Aged10aPrevalence10aRisk Factors10aYemen1 aLéonard G1 aSangare A1 aVerdier M1 aSassou-Guesseau E1 aPetit G1 aMilan J1 aM'Boup S1 aRey J L1 aDumas J L1 aHugon J00aPrevalence of HIV infection among patients with leprosy in African countries and Yemen. a1109-130 v33 a
Screening for human immunodeficiency viruses types 1 and 2 (HIV-1 and HIV-2) antibodies was carried out in the serum of 1,245 leprous patients and 5,731 controls selected in nine different centers from the Congo, Ivory Coast, Senegal, and Yemen Arab Republic. In Yemen, all sera were negative. In the Congo, the seropositivity among patients and controls was, respectively, 3.8 and 5.2%; in Senegal, it was 1.3 and 0.6%; and in the Ivory Coast 4.8 and 3.9%. Differences were not statistically significant, even considering lepromatous or tuberculoid forms (3.6% and 3.7%, respectively). HIV-2 antibodies were only detected in subjects from the Ivory Coast and Senegal. Using appropriate criteria for seropositivity (confirmation by Western blot, reactivity to HIV envelope glycoproteins) and a large selection of patients (several countries with several centers), it appears that leprosy (and specially the lepromatous form) is not a factor for HIV infection.
a0894-9255