01806nas a2200169   4500000000100000008004100001260003200042100001200074700001200086700001200098245005900110856005600169300001000225490000600235520138100241022001401622       2020                            d  bID Design 2012/DOOEL Skopje1 aLubis R1 aDarmi M1 aDewi NK00aMultibacillary Leprosy With Tumor Like Nasal Deformity  uhttps://www.id-press.eu/mjms/article/view/3248/4619  a19-220 v83 a<jats:p>BACKGROUND: Leprosy is a chronic granulomatous infection caused by Mycobacterium leprae which affects skin, peripheral nerves, and other body parts including bone, ear, eye, and nose. Nasal manifestation of leprosy may be found in the early stage with non-specific symptoms such as nasal congestion. In advanced stage, destruction of bone structures and cartilages may result in deformities. However, nasal manifestation as the only symptom in early stage can lead to delayed diagnosis.&#x0D;
CASE REPORT: We reported a case of multibacillary leprosy in a 26-year-old male with tumor like nasal deformity for 1 year and lump in the ear lobes since 8 years ago. Initially, there was nasal discharge, unfrequent epistaxis, followed by loss of smelling perception, without associated pain, or numbness since childhood. Lesions on the trunk, palms, and soles were also noted since 2 years ago. The physical examination revealed tumor with crusts and fissures on the nasal tip; accompanied by saddle nose. Slit skin smear revealed acid-fast bacilli with bacteriological index of 4+ in solid form. Hence, he was diagnosed as multibacillary leprosy with Grade 2 disability. The prognosis was poor due to permanent deformities.&#x0D;
CONCLUSION: Early diagnosis and initiation of treatment are crucial in the management of this debilitating and stigmatized disease.</jats:p>  a1857-9655