01494nas a2200169   4500000000100000008004100001260001200042100001600054700002000070700001200090245012000102856006600222300001300288490000700301520100200308022001401310       2020                            d  c01/20201 aMonteiro LD1 aMartins-Melo FR1 aPires B00aTemporal trends and spatial distribution of leprosy-related mortality in the state of Tocantins, Brazil, 2000-2015.  uhttps://www.scielosp.org/article/ress/2020.v29n3/e2018336/pt/  ae20183360 v293 a<p>Objective to describe temporal trends and spatial distribution patterns of leprosy-related deaths in the state of Tocantins, Brazil, 2000-2015. Methods this study was based on Mortality Information System (SIM) data; mortality coefficient temporal trend analysis was performed using joinpoint regression and descriptive spatial analysis, taking the state's 139 municipalities as geographic units of analysis. Results 201 leprosy-related deaths were identified in Tocantins; average mortality coefficient was 0.7 deaths/100,000 inhabitants; mortality tended to increase significantly (5.4% Annual Percentage Change - 95% CI 2.0; 8.9); the average annual crude mortality coefficient ranged from 0.00 to 6.83 deaths/100,000 inhabitants, while the smoothed indicator ranged from 0.00 to 2.42 deaths/100,000 inhabitants. Conclusion leprosy mortality showed a rising trend and heterogeneous spatial distribution in Tocantins, with the need to strengthen leprosy surveillance and control measures.</p>  a2237-9622