01242nas a2200157   4500000000100000008004100001260002700042100001400069700001500083245004900098856009200147300001000239490000700249520080300256022002501059       2019                            d  bWalter de Gruyter GmbH1 aYuniati R1 aKhrisna MB00aGlucocorticoids in Leprosy Reversal reaction  uhttps://www.degruyter.com/view/j/sjdv.2019.11.issue-3/sjdv-2019-0011/sjdv-2019-0011.xml  a77-830 v113 a<jats:title>Abstract</jats:title>
<jats:p>Leprosy is a disease that is caused by <jats:italic>Mycobacterium leprae</jats:italic> which results in lots of disabilities in the patients. Leprosy is treated by multi-drug therapy regimen; however, this therapy might cause leprosy reactions in the patients. There are several types of lepromatous reaction: type 1 reaction, type 2 reaction and neuritis. Type 1 reaction mainly occurs in BB, BL and BT forms of leprosy and is characterized by exacerbation of preexisting lesions. The therapy of this reaction according to the WHO guideline is corticosteroid therapy. This article will explain several key points related to the corticosteroid therapy in leprosy reversal reactions, including the side effects and alternative therapies available.</jats:p>  a2406-0631, 1821-0902