01673nas a2200385   4500000000100000008004100001260001700042653001500059653001000074653000900084653002400093653001000117653003800127653001100165653002200176653001600198653001100214653002100225653001200246653000900258653001600267653002500283653001400308100001300322700001700335700001400352700001600366700001600382245014600398856006200544300001000606490000700616520065000623022001401273       1990                            d  c1990 Apr-Jun10aAdolescent10aAdult10aAged10aAntigens, Bacterial10aChild10aEnzyme-Linked Immunosorbent Assay10aFemale10aFollow-Up Studies10aGlycolipids10aHumans10aImmunoglobulin M10aleprosy10aMale10aMiddle Aged10aMycobacterium leprae10aPrognosis1 aSaad M H1 aMedeiros M A1 aGallo M E1 aGontijo P P1 aFonseca L S00aIgM immunoglobulins reacting with the phenolic glycolipid-1 antigen from Mycobacterium leprae in sera of leprosy patients and their contacts.  uhttp://www.scielo.br/pdf/mioc/v85n2/vol85(f2)_053-056.pdf  a191-40 v853 a<p>For the first time in Brazil it was investigated the occurrence of IgM anti-PGL-1 in the sera of household contacts of leprosy patients using the ELISA methodology. The sera of the multibacillary patients showed significantly more immuno-reactivity than from the paucibacillary patients. It was observed a high subclinical infection incidence among household contacts (19.4%). The percentage of leprosy development was 5% (1/21) among the seropositive contact group. This finding suggests that serology could be useful as prognostic test, but for better definition is necessary to test a population from endemic area for long period time.</p>  a0074-0276