01494nas a2200349   4500000000100000008004100001260001300042653002600055653002400081653001800105653003800123653001600161653001100177653002100188653002100209653001200230653002500242653003100267653001400298100001300312700001400325700001400339700001100353700002000364700001300384700001900397245011300416300001100529490000800540520058200548022001401130       1990                            d  c1990 Jun10aAntibodies, Bacterial10aAntigens, Bacterial10aDisaccharides10aEnzyme-Linked Immunosorbent Assay10aGlycolipids10aHumans10aImmunoglobulin G10aImmunoglobulin M10aleprosy10aMycobacterium leprae10aMycobacterium tuberculosis10aTrehalose1 aCruaud P1 aPotar M C1 aDavid H L1 aPapa F1 aTorgal-Garcia J1 aMaroja F1 aOrsi-Souza A T00aIgG and IgM antibodies immunoreacting with a 2,3-diacyl trehalose-2'-sulphate in sera from leprosy patients.  a209-150 v2733 a<p>The distribution of IgG and IgM antibodies immunoreacting with the sulpholipid I (SLI) and sulpholipid IV (SLIV) of Mycobacterium tuberculosis was examined in sera from leprosy patients. It was found that the immunological reactions correlated with the clinical spectrum of leprosy; and in multibacillary patients, antibody titres declined in response to successful treatment. The serological patterns were similar to the PGL I patterns, however, the IgG responses towards the sulpholipids were predominant over the IgM responses in the case of the sulpholipid antigens.</p>  a0934-8840