01458nas a2200337   4500000000100000008004100001260001300042653001500055653001000070653002600080653001000106653002100116653003800137653001100175653001100186653002300197653002100220653001300241653001200254653000900266653001600275653002500291100002200316700001400338700001500352245007500367300001000442490000700452520064700459022001401106       1990                            d  c1990 Nov10aAdolescent10aAdult10aAntibodies, Bacterial10aChild10aChild, Preschool10aEnzyme-Linked Immunosorbent Assay10aFemale10aHumans10aImmunity, Cellular10aImmunoglobulin M10aLepromin10aleprosy10aMale10aMiddle Aged10aMycobacterium leprae1 aDhandayuthapani S1 aAnandan D1 aBhatia V N00aELISA & lepromin skin tests in household contacts of leprosy patients.  a431-60 v913 a<p>A total of 438 household contacts of leprosy patients and 228 non-contacts were studied for anti-PGL-I antibodies and cell mediated immune response to Mycobacterium leprae using ELISA and lepromin tests. The contacts showed relatively higher positivity to ELISA (29.4%) and lepromin (70.5%) as compared to non-contacts who showed 9.6 and 57 per cent positivity. In contacts as well as non-contacts the seropositivity was not found to be influenced by age and sex. However, seropositivity was higher (39.7%) in the contacts of patients with multibacillary leprosy as compared to contacts (27.7%) of patients with paucibacillary leprosy.</p>  a0971-5916