01608nas a2200289   4500000000100000008004100001260001700042653004200059653004200101653001900143653001000162653001100172653004800183653002400231653000900255653001600264653000900280100001300289700001500302700001200317245020500329300000900534490000700543050003200550520072200582022001401304       2009                            d  c2009 Apr-Jun10aAIDS-Related Opportunistic Infections10aAntiretroviral Therapy, Highly Active10aHIV Infections10aHIV-110aHumans10aImmune Reconstitution Inflammatory Syndrome10aLeprosy, Borderline10aMale10aMiddle Aged10aSkin1 aSharma P1 aBhardwaj M1 aKar H K00aInoculation leprosy and HIV co-infection: a rare case with nerve involvement preceding development of skin patch and type 1 reaction as immune reconstitution syndrome following antiretroviral therapy.  a75-90 v81  aInfolep Library - available3 a<p>The transmission of leprosy has been universally accepted to be primarily, through nasal dissemination from multibacillary patients to the susceptible persons. However, the possibility of leprosy transmission through prolonged skin contact with abraded leprous skin or through skin inoculation can not be ruled out. We report a case of development of a paucibacillary leprosy patch close to the site of a local trauma, after an interval of about 13-14 years, in a HIV positive subject. Also discussed are the various hypotheses in the aetiopathogenesis of leprosy like entry route of lepra bacilli into the body, viability of lepra bacilli in the environment and evolution of skin and nerve lesions of leprosy.</p>  a0254-9395