02245nas a2200385 4500000000100000008004100001260001300042653001500055653002800070653001700098653001100115653001100126653001000137653003000147653002100177653001100198653001100209653001100220653001100231653001000242653001200252653000900264653002600273653001300299653000900312100001500321700001400336700001200350700001400362245006400376300001100440490000800451520138600459022001401845 2010 d c2010 May10aAdolescent10aAdrenal Cortex Hormones10aAge of Onset10aBiopsy10aBrazil10aChild10aDrug Therapy, Combination10aEndemic Diseases10aFemale10aFrance10aGuinea10aHumans10aIndia10aleprosy10aMale10aRetrospective Studies10aRifampin10aSkin1 aFrémont G1 aBourrat E1 aMahé E1 aFlageul B00a[Leprosy in children: A diagnosis that must not be missed]. a359-630 v1373 a

BACKGROUND: With 254,525 new cases reported in 2007, leprosy is the worlds' second most widespread form of mycobacteriosis. According to the WHO, eradication of leprosy as a public health problem (defined by less than one case per 10,000 people) has been globally achieved. High endemic zones, however, still subsist. Leprosy rates among children, which reflect a country's endemic level, ranged from 0.55 to 19.2 % in 2006. Due to world population migrations, cases of leprosy are now seen in mainland France, in both children and adults.

PATIENTS AND METHODS: We describe three leprosy patients aged under 15 years treated at the Dermatology Unit of Saint Louis Hospital between 1st January 2002 and 31st December 2008. The three cases described account for 3 % of new patients treated for leprosy at Saint Louis Hospital over this 7-year period. All were born in an endemic country. Lesions appeared 18 months after arrival in France in two cases and clinical diagnosis was made in only one case. Due to absence of sensory loss in the lesions, diagnosis was reliant upon histopathological examination in two cases.

CONCLUSION: Leprosy should be suspected in children from endemic countries presenting skin lesions, particularly hypochromic lesions, even if there is no sensory loss, regardless of how long they have been living in France.

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