01471nas a2200277   4500000000100000008004100001260001300042653001900055653001100074653004800085653001200133100001400145700001500159700001200174700001100186700001200197700001200209700001300221700001700234245013500251856005500386300000900441490000700450520072200457022001401179       2010                            d  c2010 Jul10aHIV Infections10aHumans10aImmune Reconstitution Inflammatory Syndrome10aleprosy1 aBussone G1 aCharlier C1 aBille E1 aCaux F1 aLévy A1 aViard J1 aLecuit M1 aLortholary O00aUnmasking leprosy: an unusual immune reconstitution inflammatory syndrome in a patient infected with human immunodeficiency virus.  uhttp://www.ajtmh.org/content/83/1/13.full.pdf+html  a13-40 v833 a<p>Immune reconstitution inflammatory syndrome (IRIS) has become a frequent and potentially severe complication after initiation of following antiretroviral therapy (ART) in patients infected with human immunodeficiency virus (HIV). IRIS can unmask a previously clinically silent infection, such as tuberculosis, as recently described for Mycobacterium infections. We describe a case in a patient from Côte d'Ivoire living in France in whom skin papular lesions developed after initiation of ART. These lesions were associated with microbiologically proven leprosy. Thus, latent leprosy can appear as IRIS, and leprosy-associated IRIS should be considered in HIV-infected patients from areas endemic for leprosy.</p>  a1476-1645